Andreas Czech
Director BioNTech
Seminars
Wednesday 25th February 2026
Improving Sensitivity & Reliability of dsRNA Characterization to Prevent Immunogenicity from Trace RNA Contaminants
2:30 pm
- Mapping the spectrum of impurities in IVT mRNA (dsRNA, proteins, enzymes, nucleotides, solvents) to understand their safety and immunogenic impact
- Evaluating limitations of current antibody-based assays for dsRNA to highlight the need for greater sensitivity and reproducibility
- Embedding improved impurity detection and quantification strategies to strengthen control packages and meet regulatory expectations
