Lauren Skrajewski-Schuler PhD
Biopharma Workflow Specialist Agilent Technologies
Seminars
Thursday 26th February 2026
QC Confidence in mRNA Therapeutics: Agilent LC/MS Solutions for Endto- End Analytical Control
10:00 am
- LC/MS Analysis for QC: Agilent LC/MS workflows deliver rapid confirmation of 5′ capping, detection of poly(A) variants, and detailed sequence mapping with impurity identification using systems such as the 6545XT AdvanceBio LC/Q-TOF and 1290 Infinity III Bio LC.
- Comprehensive QC Strategy: Agilent integrates early checkpoints with various analytical methods to monitor critical quality attributes across the entire mRNA lifecycle, from IVT through formulation and release, ensuring regulatory compliance and product consistency.
- Fragment Analyzer and Orthogonal Techniques: Complementary tools deliver high-resolution nucleic acid analysis using parallel capillary electrophoresis (CE) to assess nucleic acid size and integrity, detecting incomplete or degraded RNA to support confidence in mRNA therapeutic quality.
