Manasa Chillara
Doctoral Researcher Rensselaer Polytechnic Institute
Seminars
Thursday 26th February 2026
Optimizing LNP Characterization & Storage to Enable Long-Term Stability in mRNA Therapeutics
9:30 am
- Assessing how lyophilization impacts LNP heterogeneity and functionality, and approaches to reduce variability
- Understanding how formulation variables and lipid interactions drive aggregation and stability loss during storage
- Comparing cold-chain and room-temperature strategies to evaluate trade-offs in potency, durability, and feasibility
- Establishing standardized characterization protocols to improve reproducibility, regulatory confidence, and global distribution readiness
