A Comprehensive Analysis of the mRNA-Lipid Nanoparticle (mRNA-LNP) by Capillary Electrophoresis (CE) & LC-MS
Time: 3:15 pm
day: Day One
Details:
- Calculate mRNA-LNP encapsulation efficiency with determination of purity and size of both encapsulated and unencapsulated mRNA
- Assess poly(A) tail length and profile characterization with single-nucleotide resolution
- Identify impurities in ionizable lipids with in-depth structural characterization