Elisha Fielding
Company: Sail Biomedecines
Job title: Director, Analytical Sciences
Seminars:
Overcoming the Longstanding Challenges in the Characterization & Control of dsRNA to Develop Safer & Regulatory-Compliant mRNA Therapeutics 8:35 am
dsRNA presents a significant, persistent and debated challenge in the development of safe and effective mRNA medicines. The construct-dependent nature of dsRNA formation complicates efforts to standardize production and quality control, as the absence of a standardized sensitive detection and surrogate standard hinders the establishment of universally accepted guidelines for dsRNA levels. The immunogenicity of…Read more
day: Pre-Conference Workshop Day