Thareendra De Zoysa
Company: Orna Therapeutics
Job title: Scientist
Seminars:
Advancing Potency Assay Development & Optimization for Circular RNABased Therapeutics 11:30 am
Designing and selecting an appropriate potency assay format for circular RNA-based therapies Developing and optimizing assay components to ensure accurate potency measure Characterizing the assay to ensure quality control compliance and streamline method validationRead more
day: Conference Day One
Overcoming the Longstanding Challenges in the Characterization & Control of dsRNA to Develop Safer & Regulatory-Compliant mRNA Therapeutics 8:35 am
dsRNA presents a significant, persistent and debated challenge in the development of safe and effective mRNA medicines. The construct-dependent nature of dsRNA formation complicates efforts to standardize production and quality control, as the absence of a standardized sensitive detection and surrogate standard hinders the establishment of universally accepted guidelines for dsRNA levels. The immunogenicity of…Read more
day: Pre-Conference Workshop Day